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NNMT literature links nicotinamide methylation to metabolic and methylation-pathway questions, but RUO product pages should not convert those studies into claims about a product
Note that these two documented starting doses are worlds apart in size 150 mcg versus 2.5 mg is a roughly 17-fold difference
This effect is probably mediated by both COX inhibition in the CNS and inhibition of IL-1 (which is released by macrophages during episodes of inflammation)
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