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10.1515/revneuro-2015-0016 253
Metabolic and Lipolytic Signaling Pathways Beyond anabolic signaling, IGF-1 LR3s receptor activation is linked to metabolic effects documented in research settings, including increased glucose uptake into muscle and adipose tissue via GLUT-4 transporter upregulation and enhanced amino acid transport that supports tissue repair processes
Causes may include pinched nerves in the spine, peripheral neuropathy, inflammatory neuropathies, muscle inflammation, inherited muscle conditions, thyroid disease, vitamin deficiencies, autoimmune disorders, medication-related muscle injury, and disorders of the neuromuscular junction such as myasthenia gravis
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