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Naltrexone blocks mu-opioid receptors in the hypothalamus and works to suppress appetite through a different mechanismone that may complement GLP-1 action by lowering the body's natural opioid tone related to food reward
The Core Conflict The rise of glucagon-like peptide-1 (GLP-1) receptor agonists presents a clear clinical tension: these drugs improve weight, glycemic control, and cardiometabolic risk
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