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Clinical practice recommendations for primary hyperoxaluria: an expert consensus statement from ERKNet and OxalEurope

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It is also a potent MAO inhibitor and carries an FDA boxed warning for serotonin syndrome when combined with SSRIs and similar drugs, a risk most clearly documented at intravenous and higher doses

NAC Dosing (as Glutathione Precursor) General antioxidant support: 600-1,200 mg/day in divided doses [9][18] Respiratory conditions (COPD): 600-1,200 mg/day (PANTHEON trial used 600 mg twice daily) [43][44] Psychiatric conditions: 1,200-2,400 mg/day (most trials used 2,000-2,400 mg/day) [72][73][74] Male fertility: 600 mg/day [69] Immune support in elderly: 600-1,200 mg/day [40] GlyNAC Dosing The Kumar et al