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All participants were 18 years or older, planned to initiate HCV antiviral treatment, and provided written informed consent to participate in a single-center, open-label study (ClinicalTrials.gov Identifier: NCT02734173), which was approved by The Ottawa Health Science Network Research Ethics Board (REB 2015-0305, Ottawa, Ontario, Canada)

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Removing the albumin-binding design changes clearance, duration and the shape of exposure

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