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A clinical study involving 564 adults (BMI 30-40 kg/m2, without T2DM) found that compared with orlistat (3120 mg, weight loss of 4.1 kg), LIR (subcutaneous administration of 1.2 mg/d, 1.8 mg/d, 2.4 mg/d or 3 mg/d) had an average weight loss of 4.8-7.2 kg, the two-year extended experiment of which also showed similar results (88, 89)
[10] SURMOUNT-1 : Tirzepatide for the treatment of obesity produced ~2022% weight loss over 72 weeks, among the largest effects seen in pharmacologic obesity treatment
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Nearly a month after she was diagnosed with an overdose, McClain said she was still dealing with the residual side effects, including an elevated heart rate and vision problems she felt were tied to the medication
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