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Healthcare providers in the NHS cannot restrict access to NICE approved treatments without exceptional justification

This ensures immediate bioavailability, especially for patients with absorption issues such as gut inflammation, low stomach acid, or conditions like pernicious anemia

In published preclinical work, inhibiting NNMT is associated with elevated intracellular NAD and SAM, reduced lipogenesis and smaller adipocytes in cell and diet-induced-obese rodent models, and is studied in the context of insulin sensitivity and muscle function

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