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[3] Protein kinases may possibly impact transcription factors involved in gene expression that enter the nucleus, and potentially modulate the transcription of genes associated with growth hormone synthesis and secretion

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Once released, GLP-1 helps the body to: Stimulate insulin release when blood glucose rises, which helps cells absorb sugar from the bloodstream for energy (1,2)

Preliminary investigations of GLP-1 agents in patients with both conditions have reported modest improvements in inflammatory markers, though these studies are small and not designed to establish efficacy for RA