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[44] In the cytosol [edit] Methylcobalamin and 5-methyltetrahydrofolate are needed by methionine synthase in the methionine cycle to transfer a methyl group from 5-methyltetrahydrofolate to homocysteine, thereby generating tetrahydrofolate (THF) and methionine, which is used to make SAMe

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These studies consistently show: No toxicity, even at high doses Organ-protective and regenerative benefits Absence of tumor formation, cardiovascular damage, or metabolic disruption Despite extensive animal research supporting BPC-157s safety, human safety and pharmacokinetics remain largely unstudied due to its classification as a research chemical. Sikiric, P