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O seu nome faz referncia ao mecanismo de ao inspirado na sinalizao natural da hormona GLP-1 (peptdeo semelhante ao glucagon tipo 1) , que no organismo contribui para enviar sinais de saciedade ao crebro aps as refeies
102 The GLP-1 RA and Neurogenesis Neurogenesis is a complete process in which neural stem cells (NSCs) proliferate, undergo balanced and imbalanced division to become directed progenitor cells and gradually migrate to functional areas, undergo plasticity changes, and establish synaptic connections with other neurons to generate neural function
B and C, DPP-4 inhibitors fitting into the DPP-4 catalytic site, where they interact with critical amino acid residues, including Phe357, Tyr547, Glu205, and Glu206 (87)
Huang YN, Liao WL, Huang JY, Lin YJ, Yang SF, Huang CC, Wang CH, Su PH
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