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Liposomal encapsulation of eremantholide C and goyazensolide in a sesquiterpene formulation mitigates toxicity while maintaining anti-hyperuricemic efficacy through enhanced encapsulation and sustained release, with preclinical evaluation confirming serum uric acid stabilization, excellent biocompatibility, and therapeutic potential for concurrent hyperuricemia/gout management, warranting translational investigation ( Biomimetic nanoliposomes represent a cutting-edge subset of LBDDSs
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109 The Nrf2 coordinates the basal and stress-inducible activation of the glutamate-cysteine ligase complex 110 and regulates the transcription of glutathione peroxidase 2 and glutathione S-transferases
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