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This mechanism is fundamentally different from stimulation-based lipolysis (which releases triglycerides without disrupting the cell itself): PPC produces actual reduction in adipocyte count in treated areas, making results more durable than approaches that only activate existing fat release mechanisms
however, the application is hindered by the complexity of their interaction [ 16 ]
doi:10.1136/bmjopen-2014-006592
The albumin binding creates a slow-release reservoir and prevents rapid renal clearance, extending circulation time and producing the ~6-day half-life that underpinned once-weekly dosing in trials
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