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However, TGR was unable to reduce dehydroascorbic acid or ubiquinone, compounds that are reduced by mammalian TrxR1 [49,50]
Disulfide-doped mesoporous silica nanoparticles (MSNs-ss-OH) with a high specific surface area exhibit excellent degradable properties, allowing organic silicon to decompose into small fragments containing both organic and inorganic silicon molecules in a reductive environment, thus facilitating better absorption and transport within plants [31,32,33,34]
Low adiponectin levels are linked to insulin resistance and chronic inflammation in children and adults (Nature Reviews Immunology, 2024) and respond positively to healthy lifestyle interventions (The Journal of Clinical Endocrinology & Metabolism, 2008)
In summary, the nano-iron death inhibition system, through multi-target synergistic effects, not only effectively blocks multiple key steps in lipid peroxidation but also precisely regulates the iron death process through its microenvironment-responsive characteristics
