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The addition of B12 does not boost weight loss, but may help combat the side effects of semaglutide, such as lethargy and dizziness, by promoting metabolism and increasing the availability of usable energy

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Participants averaged approximately 1.7 pounds per week during this period, with 73% achieving at least 15% total weight loss by week 24

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Lin SH, Wang J, Allen PK, Correa AM, Maru DM, Swisher SG , Hofstetter WL, Liao Z, Ajani JA

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Its also worth noting that PAPs typically require the medication to be prescribed for its FDA-approved indication, so off-label use (e.g., for weight loss without type 2 diabetes) will generally not qualify. The process also involves their healthcare provider completing and signing part of the application, which can lead to delays if theres any miscommunication or missing information, says Katy Dubinsky, PharmD, founder & CEO at VitalizeMed

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