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[Low et al 2007 1] [18] Function [edit] The activity of GSTs is dependent upon a steady supply of GSH from the synthetic enzymes gamma-glutamylcysteine synthetase and glutathione synthetase, as well as the action of specific transporters to remove conjugates of GSH from the cell

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Specifically, OUD patients receiving Ozempic have a 54% lower risk of opioid overdose than those taking metformin, a 58% lower risk than insulin alone, a 63% lower risk compared to DPP-4i, and a 42% low risk compared to SGLT2i