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In health economics and outcomes research (HEOR) and epidemiologic studies, claims data alone leave researchers without essential information such as: Body mass index (BMI) or weight trajectory to identify obesity thresholds or track improvement A1c and lipid panels to assess cardiometabolic change Liver and kidney markers such as ALT, AST, and eGFR to evaluate comorbidities like MASH or nephropathy Physician notes that document adherence barriers, recommended dosing schedules, or dietary guidance These gaps in claims mean that researchers are missing many aspects of the patient journey (Figure 1)

Moreover, interstitial glucose levels in the VMH and LH vary with blood glucose concentration [67], and these changes in glucose have been postulated to trigger meal initiation

Reduced glutathione goes into lymphoid cells, specifically lymphocytes, which are white blood cells that fight off any unknown substance in the body

It is not authorized under the Food and Drugs Act, does not carry a Drug Identification Number (DIN), Natural Product Number (NPN), or Homeopathic Drug Number (DIN-HM) issued by Health Canada, and is not intended to diagnose, treat, cure, or prevent any disease