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Furthermore, the pharmacokinetic and pharmacodynamic properties of tirzepatide at very low doses are unknown, making it impossible to predict individual responses or identify appropriate monitoring parameters

Brass EP et al

Prostate-associated gene 4 (Page4): leveraging the conformational dynamics of a dancing protein cloud as a therapeutic target

To uncover the mechanisms orchestrating the network of cell death pathways, research focuses on the identification of possible switches between distinct lethal subroutines, critically influencing the selection of a particular cell death modality acting as a connecting bridge