Even with sophisticated delivery systems, achieving oral bioavailability above 1-2% for a peptide drug was long considered an exceptional achievement
Safer DL, Adler S, Dalai SS, Bentley JP, Toyama H, Paraito S, Najarian T
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Noteworthy, these two membrane transporters are also responsible for drug uptake in the cell, further highlighting their role in developing novel anti-cancer approaches and/or improving those already existing