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Healthcare professionals should discuss this risk as part of informed consent when initiating treatment

placebo as an adjunct to intensive behavioral therapy on body weight in adults with overweight or obesity: the STEP 3 randomized clinical trial

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Selection Criteria: systematic review Inclusion criteria for the systematic review were the collection of neuroimaging (i.e., fMRI) data during exposure or reaction to reward-related stimuli in humans, combined with the measurement of endogenous levels of ghrelin or GLP-1 and/or administration of an exogenous GHS-R or GLP-1R agonist or antagonist