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In addition to GLP-1R, the peptide itself appears to be important for this interaction, as the increased levels of GLP-1 after DPP-IV inhibition (with sitagliptin) reduce nicotine consumption in male mice (Tuesta et al., 2017)
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Of note, the route of placebo administration (smoked or vaporized) was randomized across conditions A and B for each participant
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