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The single-signal approach is simpler and more predictable

More recently, analysis using the Broad Institutes Connectivity Map database identified GHK as one of the top two compounds (from 1,309 bioactive molecules screened) recommended for study in aggressive metastatic colon cancer models, with GHK upregulating expression of numerous caspase genes and DNA repair genes associated with anti-cancer activity

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To assess heterogeneity among the studies, we utilized the chi-square statistic and calculated I 2