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The dose increases typically occur every four weeks, and many people find their optimal dose somewhere in the middle of the range rather than necessarily at the maximum

Eating smaller, more frequent meals throughout the day can help to regulate appetite and prevent overeating

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Factors that may contribute to reflux symptoms with semaglutide include: Prolonged gastric retention increasing intragastric pressure Nausea and retching, which can compromise sphincter integrity Changes in eating patterns and meal composition Pre-existing gastroesophageal reflux disease (GERD) that becomes symptomatic Clinical experience and patient reports suggest that some individuals do develop new-onset reflux symptoms or experience worsening of pre-existing GERD after initiating semaglutide therapy