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In the GHK-Cu complex, the copper ion coordinates with multiple binding sites: the nitrogen from the histidine imidazole side chain, the alpha-amino group of glycine, the deprotonated amide nitrogen of the glycine-histidine peptide bond, and oxygen from the lysine carboxyl group, forming a square-planar pyramid configuration
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Gao W, Liu L, Huh E, Gbahou F, Cecon E, Oshima M, Houz L, Katsonis P, Hegron A, Fan Z, et al
Systemic IGF-1 administration can lead to profound hypoglycemia, especially in the fasted state. LeRoith, D
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