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PMID: 25407511 Written by Ali Rza Akn Microbiome Scientist, Author & Founder of Next-Microbiome Ali Rza Akn is a microbiome scientist with nearly 30 years of experience in translational biotechnology, systems biology, and applied microbiome research, spanning discovery, preclinical development, and clinical-stage translation

The European Association for the Study of the Liver (EASL) clinical practice guidelines on Wilson disease note that hepatic copper exceeding 250 mcg/g dry weight is a strong diagnostic criterion for Wilson disease, but subclinical copper accumulation can begin at much lower thresholds in patients with cholestatic or cirrhotic liver disease [2]

Under the Human Medicines Regulations 2012, it is illegal to sell or supply a medicinal product in the UK without a valid Marketing Authorisation

Side effects and cautions B12 has no established upper limit due to low toxicity, but injections can have side effects: Common: soreness, redness or swelling at the injection site