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Brenner added, this also meant the mice could not develop any autoimmune disease such as multiple sclerosis. Further tests confirmed that the mice cannot produce any GSH in their T cells, and indicated that several signaling events that directly boost metabolism and increase energy consumption are lacking
This suggests the health of the pancreas prior to drug initiation may be an important determinant of the rate of proliferation with GLP-1RA treatment
The drug is approved in three different forms for treating T2DM by the US Food and Drug Administration (FDA)
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