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Typically, before a drug can be marketed, it must pass through a series of clinical trials, in order to identify safe dosages and to determine that any positive outcomes are due to the substance itself, and not to bias in the study design
However, topical products often contain additional ingredients that may cause reactions independent of the copper peptide itself
Homozygous mice embryos with knockout of the heavy subunit fail to gastrulate and die before day 8.5 of gestation [13]
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