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The FDA approves them based on a series of clinical trials that prove efficacy and most importantly safety
& Chance, B
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Adequate B12 status is necessary for normal cellular function, but supraphysiological dosesbeyond correcting deficiencydo not demonstrably enhance metabolism in individuals with normal B12 levels
This is why some formulation scientists recommend slightly acidic buffer solutions for peptide storage when long-term stability is needed
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