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If a GLP-1 is being prescribed for a different condition such as type 2 diabetes or cardiovascular disease risk reduction it would be handled through the standard Part D benefit, not the Bridge program
Stanford suggests considering the following alternatives: Phentermine/topiramate ER (which has stronger efficacy and is FDAapproved for long-term use) GLP1 receptor agonists (e.g., semaglutide) Dual GLP1/GIP agonists (e.g., tirzepatide) Naltrexone/bupropion Orlistat in select cases The bottom line on phentermine for weight loss Phentermine can be an effective, affordable option for jump-starting weight loss, especially if you need short-term appetite support and pair it with a healthy diet and exercise
CNS/GI Medications : Opioids and anticholinergics can worsen GI side effects, while timing adjustments may be needed for some antidepressants or corticosteroids
Overall, the extent to which GLP-1RAs cross the bloodbrain barrier remains uncertain in pre-clinical studies 4 , and further discrepancies are expected in translating these data from animals to humans
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