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Trikkalinou, A., Papazafiropoulou, A
The T[SH] 2 molecules deliver reducing equivalents to peroxidases and other enzymes responsible for neutralizing ROS, and the oxidized form of trypanothione is reduced by trypanothione reductase (TryR) in presence of NADPH produced by the pentose phosphate pathway (PPP) (discussed below and reviewed in Irigon et al., 2008)
After reconstitution, follow established laboratory storage procedures to help maintain peptide stability
Liposomal oral formulations extend half-life 16.8-fold compared to native GSH, offering sustained release despite slower initial absorption
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