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Concentrations of vitamin C can be 50 times higher when delivered by IV infusion rather than through oral supplements
Taken together, in vivo knock-in of scExe4 effectively mitigates long-term body weight gain in non-genetic DIO mice models, demonstrating the potent metabolic effects of secreted Exe4 against DIO
However, some of the most significant interactions are with other GLP-1 drugs like Wegovy, the antiviral drug cidofovir, other diabetes medications like sulfonylureas or metformin, loop diuretics, quinolone antibiotics, and aminoglycoside antibiotics
doi: 10.3389/fmicb.2025.1549499
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