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Table of Contents Origins of the Pancreatic Safety Concern What Long-Term Data Reveal Absolute vs Relative Risk in Context Practical Guidance for Patient Counseling Origins of the Pancreatic Safety Concern Early safety signals suggesting a pancreatic cancer risk with GLP-1 receptor agonists emerged shortly after these drugs were introduced for type 2 diabetes
It was reported that the same VDR polymorphism in mothers without ASD may increase the risk of giving birth to a child with ASD [100]
With time, however, evidence has surfaced to suggest the drug's reach could go far beyond that, meaning metformin might be having an unseen effect in millions of patients worldwide
