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In silico analysis of the amaranth globulins with tryspin identified four peptides, which contained thirteen to fifty amino acid residues (11S amaranth globulin f(113), f(1839), f(6981), f(92143)) and which may be responsible for the inhibitory activity

This gives Mounjaro a slight advantage in achieving faster weight-loss results. In a head-to-head clinical trial, Lilly reported that tirzepatide led to an average weight reduction of 20.2%, compared to 13.7% with semaglutide after 72 weeks of treatmenta 47% greater relative weight loss with tirzepatide