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Under acidic conditions (pH 5.0), the release rate reaches 93%, allowing efficient intracellular delivery of rutin

They emphasize that future work must determine if these observed benefits hold for older patients with pre-existing conditions like sarcopenia (age-related muscle loss) and other conditions associated with wasting or frailty

Biochem Med Metab Biol 45:244253 Chalmers RA, Roe CR, Stacey TE, Hoppel CL (1984) Urinary excretion of l-carnitine and acylcarnitines by patients with disorders of organic acid metabolism: evidence for secondary insufficiency of l-carnitine

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