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Clinical trials demonstrate significant efficacy, with semaglutide showing average weight loss of approximately 15% in the STEP trials and tirzepatide achieving up to 20% weight loss in the SURMOUNT trials, though individual responses vary considerably

FEBS Lett Watanabe N, Matsumoto S, Suzuki S, Fukaya T, Kato Y, Hashiya N (2020) Effect of Ergothioneine on the Cognitive Function Improvement in Healthy Volunteers and Mild Cognitive Impairment Subjects A Randomized, Doubleblind, Parallelgroup Comparison Study

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