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Common components youll hear about: B12 (vitamin B-12): involved in normal nerve and blood cell function
How 5-Amino-1MQ Affects NNMT A 2017 medicinal-chemistry study screened N-methylated quinolinium, isoquinolinium, pyridinium, and benzimidazolium/benzothiazolium analogues for NNMT inhibition
Key considerations if a patient discloses combined use include: Gastrointestinal effects : Both agents may independently cause nausea, vomiting, or appetite suppression
It competes with nicotinamide (NAM) for the active binding site of NNMT, preventing the enzyme from catalyzing the transfer of a methyl group from SAM to NAM
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