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The downsides: portions are small even by GLP-1 standards, subscription is required, and shipping is $19.95 per order
Patients should be counseled about contraception (with backup methods during tirzepatide initiation/dose increases), hydration to prevent kidney injury, and monitoring for gallbladder symptoms
Other skin manifestations may include psoriasis, which presents as scaly patches, or scleroderma, which can cause skin to harden and tighten
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