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Even a modest reduction of 5 to 15% in total body weight for those grappling with excess weight brings about significant benefits, notably in curbing risk factors, especially for heart disease
Interestingly, nanoparticle (NP)-induced cell death has been described recently as being consistent with the new 5 R principle
The dual glucose-dependent insulinotropic polypeptide/GLP-1 agonist tirzepatide sold as Mounjaro for type 2 diabetes started rolling out in 2022
Furthermore, GLP-1s also have been shown to reduce cardiovascular risks, as well as potentially providing a range of other health benefits for patients with chronic kidney disease, gastrointestinal disorders, neurodegenerative diseases and psychiatric disorders
