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During plasmapheresis, approximately 650-850 millilitres of plasma is collected (depending on your weight), with red blood cells returned to your circulation along with a replacement fluid, according to NHSBT procedures

Worryingly however, 26.8% of patients had to discontinue the trial due to the severity of side-effects, although it must be noted that this was in part due to the lack of a run-in (A time frame where drug dosage is started from a low dosage and then escalated over time until the highest tolerable dose for the patient is reached) [40]