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In short, despite some heterogeneity across the trials, GLP-1 receptor agonists were shown to reduce the hazard ratios [95%CI] for 3-MACE by 12 [618]%, cardiovascular death by 12 [419]%, myocardial infarction by 9 [016]% and stroke by 16 {724]%
Vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) see dose-dependent increases, promoting the blood vessel formation necessary to support new tissue growth
This is where the blood vessels grow abnormally under the retina and become leaky fluid
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