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These findings suggest that DMF, in addition to NRF2 activation on antioxidant response, could affect L2HGDH expression, L2HG and SAM levels to modify DNA 5mC and 5hmC modifications and CBS expression in SCD erythroblasts
Fernandes GFS, Silva GDB, Pavan AR et al (2017) Epigenetic regulatory mechanisms induced by resveratrol
The net result is a shift toward fat oxidation rather than fat storage
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