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Risk Factors for Developing IC While anyone can develop IC, certain factors increase risk: Gender: Women are significantly more likely to develop IC Age: Most common onset between 30-40 years Fair skin and red hair: Higher prevalence noted Chronic pain conditions: Fibromyalgia, irritable bowel syndrome (IBS), chronic fatigue syndrome Autoimmune disorders: Lupus, Sjgrens syndrome, rheumatoid arthritis History of UTIs: Frequent infections may contribute Allergies: People with multiple allergies show higher IC rates Anxiety and depression: May coexist with or contribute to IC The IC-Inflammation Connection Recent research emphasizes the role of chronic inflammation in IC development