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GR is a ubiquitous 100-120 kDa dimeric flavoprotein that catalyzes the reduction of oxidized glutathione (GSSG) to reduced glutathione, using beta-nicotinamide dinucleotide phosphate (NADPH) as the hydrogen donor

In preclinical and in-vitro investigations, the amylin component has been examined for its activity at amylin and calcitonin receptors in hindbrain regions such as the area postrema, where research models associate it with modulation of food-intake signaling and gastric emptying

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Univariate comparisons between patient groups were analyzed using the Students t -test or the MannWhitneys U-test, as appropriate