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2012;98:16206.e1

Women have reduced physiological function

Metabolic impact : The mechanisms by which these medications improve insulin secretion, suppress glucagon, delay gastric emptying, and reduce appetite are all dose-related

Two additional mu class enzymes, GST M1-1 and GST M5-5, show 20% of the GST M2-2 activity, and the alpha class members GST A1-1 and GST A2-2 are almost as active (Table 1)