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This is one of the most common degradation pathways and one of the hardest to detect visually

Despite extensive evidence for GLP-1R's neuroprotective and anti-inflammatory effects, fundamental gaps remain in understanding how these responses are orchestrated at the cellular level

Recently, through the engagement of their respective receptors, studies have shown that GIP and GLP-1 have a synergistic effect on appetite and body weight when the peptides are combined in pharmacology [6, 8], but the exact mechanisms underlying the enhanced weight loss exhibited by GIPR/GLP-1R co-agonism are still to be elucidated

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