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Reduced Glucagon Secretion: Semaglutide GLP-1 decreases glucagon release, a hormone that raises blood sugar, thus preventing unnecessary glucose release from the liver

Dermatology Research and Practice, 2011 , 379173

When GLP-1 activates receptors in your hearts upper chambers (called the atria), it causes these chambers to release a hormone called ANP (atrial natriuretic peptide)