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For instance, GnRH from the hypothalamus stimulates pituitary secretion of LH and FSH, which act upon the ovaries and testes

They provide an estimate of equivocal dosages to minimize the risk of underdosing or overdose, maximize efficacy, and reduce GI side effects

Carnitine Health Professional Fact Sheet. Available at: NCCIH

The modifications do two things: they make it far longer-lasting (active for roughly a day instead of minutes) and much harder for your body to switch off