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Hyaluronidase, collagenase, and elastase are commonly used to degrade the fibrotic soft tissue matrix, although these enzymes lose their activity completely over a short period 18
It spills over beyond appetite, hitting mood and blood sugar, too
doi: 10.1021/acsami.5c08888 58 LuoTFanZZengAWangAPanYXuY
The authors noted limitations including reliance on ICD codes to identify NAION, lack of data on diabetes duration prior to Medicare enrollment, and a restricted age range that may limit generalizability
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