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It may feel tender when pressed, particularly if it has become mildly inflamed
LEADER [29] and SUSTAIN-6 [30] reported a prespecified renal composite of new onset or persistent macroalbuminuria, persistent doubling of serum creatinine and eGFR 45 mL/min/1.73 m 2 , need for renal replacement therapy (RRT), and renal death
However, this should always be done under expert medical guidance to avoid overstimulation or hormonal imbalances
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