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Meanwhile, the PD group had the highest levels, followed by the progressive supranuclear palsy (PSP) group and then the MSA group, compared with the control group (Yamagishi et al., 2018)

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Frontiers in Cellular and Infection Microbiology , 11

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The accumulation of LCACs during mitochondrial FAO disorders can inhibit the activity of PPAR/PGC1, destroy the regeneration of peroxisomes, lead to increases in BCAA and ROS levels, and activate the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway

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