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although human relevance remains uncertain, patients with a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia type 2 (MEN2) are generally advised not to use GLP-1 RAs
If it worsens or is accompanied by heat, pain, or fever, seek evaluation
Kisspeptin can selectively increase LH to induce ovulation without generally increasing estrogen or testosterone systemically
GLP-1 receptor agonists are glucose-dependent, meaning they enhance insulin secretion only when blood sugar is elevated
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